In issue 5 of Patrick Horvath's series, the town of Woodbrook turns on Sam Strong, the serial-killer bear, and she has to leave town on her own.
From The Publisher
Sam’s foe was quick and mighty clever. Now Sam must skip town, maybe forever. The town doesn’t trust her, they think she’s the one. So Sam’s on her own, and alone she must run. But maybe, just maybe, she’ll learn in the wild. And return to that town, to face the devil child.