Published in 2001 by DC Comics, Joker: Last Laugh is a six-issue limited series written by Chuck Dixon and Scott Beatty with art by Pete Woods. The story follows the Joker after he discovers he has a terminal brain tumor.
Believing he has nothing to lose, the Joker embarks on a final spree of chaos. He uses a special Joker venom to jokerize other villains, turning them into insane versions of themselves. This leads to widespread chaos across the DC Universe, involving Batman, Nightwing, and Oracle.
The series had several tie-ins across DC titles, making it a significant crossover event. The storyline culminates in a showdown between the Joker and Batman.