X-Factor #222 was published by Marvel Comics on September 1, 2011, as part of a series that began in 2006. Peter David writes, and art comes from David Yardin, Emanuela Lupacchino and Guillermo Ortego. This 36-page issue features Wolfsbane, Madrox, M, Siryn and Rictor, among 17 characters cataloged on VerseDB.